Our understanding of the complex process of aging has benefitted greatly
from experimental evolution. The traditional animal models for human aging, however,
are all characterized by “fast” life-histories, with rapid development, short lifespan and
intensive, early investment in reproduction. This is in sharp contrast to the characteristics
of the human life history and so may lead to inappropriate extrapolations about
processes important in human aging. In response to these challenges and for better
understanding and intervening in processes fundamental to aging in humans, I propose
programs of experimental evolution for both delayed reproduction and for accelerated
development in a bat species with a significantly slower life history than traditional
animal models for human aging.

• Generating insights into human aging from experimental evolution using bats (or other “slow” life history species)